Image

A Study to Test Whether BI 1356225 Improves Impulsive Behavior in People With Opioid Use Disorder Who Are Taking Buprenorphine

Testing if BI 1356225 helps impulsivity in opioid users on Buprenorphine.

Recruiting
18-65 years
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is for adults aged 18-65 who have an opioid use disorder, also known as opioid addiction. They must already be taking a medicine called buprenorphine. The study aims to see if a new medicine, BI 1356225, can help control impulsive behavior, which is when people act without thinking about the risks.

Participants are randomly placed into two groups: one takes BI 1356225, and the other takes a placebo, a pill that looks the same but has no medicine in it. They take one pill a day for 8 days and continue their regular buprenorphine treatment.

The study lasts up to 6 weeks and includes 3 visits to the study site. At one visit, participants stay for 9 nights. Doctors will check if the new medicine helps with impulsive behavior by using tasks on a computer and asking questions. They will also monitor for any side effects.

  • Participants stay at the study site for 9 nights during one visit.
  • The study lasts up to 6 weeks with 3 total visits.
  • Participants must continue taking buprenorphine throughout the study.
Print
Study details
    Opioid Use Disorder

NCT06628622

Boehringer Ingelheim

7 March 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.