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A Study of Auxora in Patients With AKI and Injurious Lung "Crosstalk"

Exploring Auxora's effects on kidney and lung health.

Recruiting
18 years and older
All
Phase 2

This study looks at the effects of a drug called Auxora in people with acute kidney injury (AKI) and breathing problems known as acute hypoxemic respiratory failure (AHRF). AKI means the kidneys suddenly stop working well, and AHRF means having very low oxygen levels in the blood. Up to 150 patients will participate, with some receiving Auxora and others a placebo, which looks the same but has no active medicine. The study will have 5 drug infusions over 5 days. Both doctors and patients won't know who is getting Auxora or the placebo.

  • The study lasts until Day 90 with regular hospital checks.
  • Participants must be at least 18 and have Stage 2 or 3 AKI.
  • Pregnant or nursing women cannot participate.
Study details
    Acute Kidney Injury

NCT06374797

CalciMedica, Inc.

21 June 2025

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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