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Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

Study on quizartinib or placebo with chemo for new FLT3-ITD negative AML.

Recruiting
18-70 years
All
Phase 3

This study is for adults with newly diagnosed acute myeloid leukemia (AML), a type of blood cancer. Researchers are testing a medicine called quizartinib to see if it helps people live longer when combined with chemotherapy. Some people will get quizartinib, while others will get a placebo, which looks like the medicine but has no active ingredients. The study will last up to 36 cycles of treatment. To participate, you must be between 18 and 70 years old and not have a specific gene change called FLT3-ITD.

Key Points:

  • Participants will receive either quizartinib or a placebo, alongside chemotherapy.
  • The study includes up to 36 cycles of treatment.
  • Participants must not have certain types of leukemia or have had previous AML treatment, except for limited allowances.
Study details
    Leukemia

NCT06578247

Daiichi Sankyo

7 March 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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