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A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)

Exploring Remternetug for early Alzheimer's in TRAILRUNNER-ALZ 3 study.

Recruiting
55-80 years
All
Phase 3

This study tests a drug called Remternetug (LY3372993) for early Alzheimer's Disease (AD), which affects memory and thinking. The study compares Remternetug to a placebo (a harmless, inactive substance). It aims to see if Remternetug helps delay or prevent memory and thinking problems.

The study lasts up to 255 weeks, which includes different phases like screening, treatment, and observation. Participants who initially receive a placebo may later get the actual drug. To join, you need to have certain test results and a partner who knows you well. People with serious illnesses or other conditions that might interfere with the study can't participate.

  • Duration: Participation could last nearly 5 years (255 weeks).
  • Visits: Various visits required during the study phases.
  • Eligibility: Specific criteria must be met, such as no severe allergies or other conditions.

Discuss with your doctor if this study is suitable for you, especially if you have early AD and meet the necessary criteria.

Study details
    Alzheimer's Disease

NCT06653153

Eli Lilly and Company

28 June 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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