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EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

EPIC-Peds: Studying COVID-19 medicine for at-risk kids under 18.

Recruiting
17 years and younger
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study aims to learn about a medicine called nirmatrelvir/ritonavir for treating COVID-19 in kids under 18 who are not in the hospital but could get very sick. Researchers want to see how safe it is, how the body processes it, and how well it works. To join, kids must have tested positive for COVID-19 in the last 72 hours and started showing symptoms within the last 5 days. They cannot have been hospitalized for COVID-19, have certain serious health issues, or be on some other medications.

  • The study focuses on kids under 18 with COVID-19 who are at risk of severe disease.
  • The medicine's safety and effectiveness are being tested.
  • Participants should not have been hospitalized for COVID-19 or have specific health conditions.
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Study details
    COVID-19

NCT05261139

Pfizer

19 July 2025

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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