EPIC-Peds Study is looking at how a medicine called nirmatrelvir/ritonavir works in kids under 18 who have COVID-19 but are not in the hospital. The medicine is given to kids who might get really sick from COVID-19. The study checks if the medicine is safe, how it moves in the body, and how well it works. Pharmacokinetics is a fancy word for how the drug changes and leaves your body.

Kids can join if they have COVID-19, are under 18, and have some risk of getting very sick. They can't join if they've been in the hospital for COVID-19 or have other serious health issues. Girls who are pregnant or breastfeeding can't join either.

• The study is for kids who are not hospitalized but at risk of severe COVID-19.
• Participants must have a confirmed COVID-19 infection within 72 hours before joining.
• Excludes those with certain health conditions or on specific medications.