This study tests a medicine called BI 1569912 in adults aged 18-65 with major depressive disorder (MDD). MDD is a type of depression that can affect how you feel and think. Participants are randomly placed into 4 groups: three groups receive different doses of BI 1569912, and one group gets a placebo, which looks like the medicine but has no drug in it. Participants take their tablets once daily for 6 weeks.

The study lasts about 2.5 months, during which participants visit the study site at least 7 times. At these visits, doctors check participants' depression symptoms and overall health. They also observe any unwanted effects of the medicine.

• The study lasts about 2.5 months, with at least 7 visits to the study site.
• Participants are randomly assigned to different groups to test medicine doses.
• Doctors monitor health and symptoms throughout the study.