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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

Testing Suzetrigine for diabetic nerve pain relief and safety.

Recruiting
18-80 years
All
Phase 3

This study looks at how well and safely **Suzetrigine**, a new medicine, works for people with pain from **diabetic peripheral neuropathy (DPN)**. DPN is a problem where diabetes causes nerve damage, often leading to pain in the feet and legs. If you join, you need to weigh at least 45 kilograms, have a body mass index (BMI) between 18 and 40, and have diabetes with pain in both legs. Your average daily pain score should be between 4 and 9 during the first week. You cannot join if you have been in another Suzetrigine study or have more than 3 missing pain scores in the first week.

  • The study checks if Suzetrigine helps reduce pain safely.
  • Participants must have diabetes with leg pain and meet weight and BMI requirements.
  • You cannot join if you've been part of a Suzetrigine study before.
Study details
    Diabetic Peripheral Neuropathic Pain

NCT06628908

Vertex Pharmaceuticals Incorporated

28 June 2025

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