This study tests if a new treatment, called **V940**, helps stop melanoma, a type of skin cancer, from coming back. V940 is a special medicine made just for you, called an _individualized neoantigen therapy_ (INT). It's used with another medicine called **pembrolizumab**. Pembrolizumab helps your immune system fight cancer. Researchers want to see if using both medicines is better than just using pembrolizumab alone.

To join this study, you must have had surgery to remove melanoma and not have taken any other cancer medicine. Your cancer must be at Stage IIB, IIC, III, or IV, meaning it's more serious but not spread everywhere. If you have another type of cancer, have had heart issues recently, or had a bad reaction to similar medicines, you might not be able to join.

• The study involves taking V940 plus pembrolizumab or just pembrolizumab.
• Doctors will check if the cancer comes back after treatment.
• You must meet specific health criteria to participate.