This study looks at whether a new drug, Rezafungin, is effective and safe for preventing serious fungal infections in adults getting a blood and marrow transplant. Blood and marrow transplants are used to treat various diseases where the blood cells or bone marrow are damaged or not working properly. Rezafungin will be compared to the usual treatment given to prevent these infections. The study is double-blind, meaning neither the doctors nor the patients know who is receiving Rezafungin or the standard treatment.
- Participation: You must be at least 18 years old and getting a matched blood and marrow transplant.
- Visits: The study involves multiple visits to the hospital, especially during and after the transplant.
- Risks: Some people may experience side effects like allergic reactions or other health issues.
Before joining, you’ll have medical checks to ensure your liver and kidneys are working well. You’ll also need to agree to certain conditions regarding birth control if you're of child-bearing potential. This study lasts about 90 days after your transplant.