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A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma

Exploring new treatments for advanced pancreatic cancer.

Recruiting
18 years and older
All
Phase 1/2

This clinical trial is for patients with advanced pancreatic cancer, testing two treatments: **Ivaltinostat** and **Capecitabine**. Pancreatic adenocarcinoma is a type of cancer in the pancreas, an organ that helps with digestion. **Ivaltinostat** is a new drug being studied that may help treat this cancer. **Capecitabine** is an existing cancer medicine in pill form. The study has two phases. In Phase 1b, the study will determine the best dose of Ivaltinostat to use with Capecitabine. In Phase 2, patients will randomly receive either both drugs or just Capecitabine. Eligible participants must have had prior treatment with a specific chemotherapy called **FOLFIRINOX** without their disease getting worse. The study will check how well the tumor responds every 6 weeks. If you join, you'll need to visit the clinic regularly for treatment and check-ups.

  • The study lasts several months with regular clinic visits.
  • Participants receive either one or both medications.
  • Safety and side effects will be closely monitored.
Study details
    Metastatic Pancreatic Adenocarcinoma

NCT05249101

CG Pharmaceuticals, Inc

1 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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