We're studying if giving a lot of fluids through an IV (hyperhydration) can help kids with a specific type of E. coli infection called STEC. This infection can sometimes cause a serious condition called hemolytic uremic syndrome (HUS), which can harm the kidneys. Right now, doctors usually wait and see before giving fluids to avoid too much fluid in the body. We're comparing this usual method to hyperhydration to see which is better for kidney health and fewer other problems.

• The study can last up to 30 days, and participants will be closely monitored for kidney health and other complications.
• The study targets kids aged 9 months to under 21 years with high-risk STEC infection signs like bloody diarrhea.
• Participants will help us understand if hyperhydration is a better treatment method and contribute to future research.

Kids who had HUS before, have certain chronic diseases, or are more than 10 days from the start of symptoms can't join. If you want to join or know someone who might, make sure they fit the criteria and talk to a doctor.