The study aims to create a database to help doctors provide better care for patients with pancreatic cancer. It looks at the treatment called **Pancreatic Irreversible Electroporation (IRE)**. This is a method that uses electrical pulses to destroy cancer cells and is used when the tumor cannot be surgically removed. The study examines how well IRE works and its potential risks or complications. To join, participants must be at least 18 years old, have pancreatic cancer, and be eligible for this type of treatment. Those with certain heart devices, recent heart attacks, or metal implants near the cancer cannot join. The study involves **following up for up to 2 years** to track treatment results. Each participating center must get approval and collect patient data securely.

• The study requires **up to 2 years of follow-ups**, typically every 3-6 months.
• Data entry will be **web-based** and include comprehensive details of the treatment and follow-ups.
• Participants' personal information will be de-identified to ensure **privacy**.