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A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Studying HIV treatment combining antibodies and ART in early infection.

Recruiting
18-70 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing new treatments for people with acute HIV infection (AHI). HIV is a virus that attacks the immune system. The study will check if adding special antibodies (bNAbs), which can fight HIV, to regular HIV medicine (ART) is safe and effective. People in the study will be split into two groups. One group will get both bNAbs and ART, and the other will get a placebo (a harmless substance) and ART.

The study involves 48 adults who haven't started ART yet. You must follow certain health and safety rules to join, like not having certain diseases or conditions. Women who can get pregnant must use birth control.

  • Study Time: You must be able to attend regular visits during the study.
  • Compensation: The study might offer payment for participation.
  • Risks: Possible side effects from the new treatment, like allergic reactions.

Your involvement will help researchers understand if this new treatment can help control HIV better. If you're interested and meet the requirements, you can participate with your doctor's guidance.

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Study details
    Acute HIV Infection

NCT05719441

National Institute of Allergy and Infectious Diseases (NIAID)

1 April 2025

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What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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