This study is to see how well and safe a medicine called **BLU-5937** works for adults with a stubborn cough that doesn't go away, called **Refractory Chronic Cough (RCC)**. It's a **52-week** study, meaning it will last for about a year. The study is randomized (participants are randomly chosen to receive BLU-5937 or a placebo, which is a fake pill), double-blind (neither the participants nor the researchers know who gets the real medicine), and placebo-controlled (some participants receive a placebo to compare results). The main goal is to see if BLU-5937 reduces coughs over a 24-hour period after 12 weeks. To join, you must have had this cough for at least one year and, if you're a woman who can have children, use effective birth control during the study and 14 days after the last dose. You can't join if you're a current smoker, have certain lung diseases, had a recent respiratory infection, or other severe conditions.

• The study lasts for 1 year.
• Participants will be randomly assigned to receive the medication or a placebo.
• Women must use effective contraception during and after the study.