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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Study testing BGB-16673 for B-cell cancer patients.

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This research study is testing a new medicine called **BGB-16673** for certain types of blood cancers called **B-cell malignancies**. These include conditions like **Marginal Zone Lymphoma (MZL)**, **Follicular Lymphoma (FL)**, and others. The study has two parts: the first part is to find the right dose (Phase 1), and the second part tests this dose on more people (Phase 2). If you join, you will help test how safe BGB-16673 is and find the best dose.

  • You must have a specific type of B-cell cancer and have tried certain treatments before.
  • The study will last for several months and requires regular visits for tests and check-ups.
  • There may be risks or side effects, so it’s important to talk to your doctor.

Some people cannot join, like those with other cancers or brain involvement. It’s important to discuss your health history with the study team to see if you qualify. This study offers a chance to try a new treatment that could help others in the future.

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Study details
    B-cell Malignancy
    Marginal Zone Lymphoma
    Follicular Lymphoma
    Non-Hodgkin Lymphoma
    Waldenström Macroglobulinemia
    Chronic Lymphocytic Leukemia
    Small Lymphocytic Lymphoma
    Mantle Cell Lymphoma
    Diffuse Large B Cell Lymphoma

NCT05006716

BeiGene

4 May 2025

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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