This study is testing a new treatment, VP-315, for basal cell carcinoma (BCC), a type of skin cancer. **Basal cell carcinoma** is a cancer that starts in the basal cells, which are found in the skin's lower layer. The study will involve about 80 adults who have at least one BCC spot confirmed by a biopsy, which is a small sample of tissue taken to be checked under a microscope.

Participants will receive VP-315 as an injection directly into their BCC spots. The treatment cycle is a week long, with injections on up to 3 days and 4 days of rest. The goal is to find out how safe and effective different doses of VP-315 are.

• The study lasts several weeks; participants must refrain from certain activities and products.
• Participants will have to visit the study center several times for treatment and check-ups.
• Participants must use effective birth control during and for four weeks after the study.