Veterans with PTSD, a condition often caused by severe trauma, may suffer from insomnia, which makes it hard to sleep. This study will test if medications like trazodone and eszopiclone can help with sleep issues. PTSD can cause nightmares, flashbacks, and irritability. The study will compare these medications with a placebo, which is a pill without medicine, to see if they help. The study will last about 17 weeks, with the first 3 weeks adjusting the medication dose. Participants must be Veterans with PTSD and insomnia, ages 18-75. They'll be randomly given either trazodone, eszopiclone, or placebo.
- The study requires about 17 weeks of participation.
- Participants will either receive medication or a placebo.
- Participants should secure firearms during the study for safety.
Participants must not have certain medical conditions or be in other medical studies. Females must use birth control and agree not to become pregnant during the study. The study will measure changes in sleep and PTSD symptoms, using various scales and questionnaires.