Image

Short-Term Linvoseltamab Treatment on Top of Chronic Dupilumab Treatment for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy

Testing Linvoseltamab with Dupilumab for severe food allergies in adults.

Recruiting
18-50 years
All
Phase 1

This study is testing a new drug called linvoseltamab combined with another drug, dupilumab, for adults with severe food allergies. A food allergy happens when your immune system overreacts to certain foods, producing IgE antibodies (IgE stands for Immunoglobulin E), which can cause allergic reactions. The study aims to check if this combination is safe and how it affects the body.

To join, you must have a severe food allergy and be on dupilumab for some conditions or willing to start it. The study will look at any side effects of the drugs and how they change the levels of different antibodies in the blood. Participants will also need to use an epinephrine auto-injector and may require vaccinations.

  • The study requires you to continue dupilumab treatment for its duration.
  • Participants must not have certain health conditions, like asthma or infections.
  • People who are pregnant or breastfeeding cannot join.

If you think you qualify and are interested, consider discussing with your doctor.

Study details
    Food Allergy

NCT06369467

Regeneron Pharmaceuticals

1 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.