Study Purpose: This study is being conducted to see if a drug called ziltivekimab can help people with heart failure and inflammation. Heart failure is when the heart doesn't pump blood as well as it should, and inflammation is when the body is trying to heal but might cause swelling or redness.
How the Study Works: Participants will receive a monthly injection, either of ziltivekimab or a placebo (a harmless substance with no medication). The injections can be given using a pre-filled syringe into a skinfold or a pen-injector into flat skin. The study will last up to 4 years, and participants will attend up to 20 clinic visits. Participants will also use a study app on their phone to record their injections and fill out surveys.
- Duration: The study lasts up to 4 years with up to 20 clinic visits.
- Participation: Requires using a phone app to record injections and answer questions.
- Considerations: Some people may get a placebo instead of the actual drug.
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