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A Dose Range-Finding Study to Assess the Efficacy and Safety of Multiple Dose Levels of AZD8630 in Adults With Uncontrolled Asthma at Risk of Exacerbations

Exploring safe doses of AZD8630 for adults with uncontrolled asthma.

Recruiting
18-80 years
All
Phase 2

This study tests a new asthma medicine, AZD8630, given through a special inhaler. It's for adults with serious asthma not well controlled by their current inhalers. The study checks how safe and effective AZD8630 is, using different doses. It lasts up to 57 weeks, with a main treatment phase up to 52 weeks. Around 516 participants will join from 20 to 25 countries.

To qualify, you must be 18 to 80 years old, have had asthma for at least a year, and a history of asthma flare-ups in the past year. You can't join if you have other serious lung diseases, recent asthma treatment, or certain heart problems. Also, participants must use effective birth control during the study.

  • Study duration: up to 57 weeks.
  • Conducted in 220 centers worldwide.
  • Requires commitment to regular visits and tests.

Joining helps understand how well AZD8630 works, but there are risks, like any new treatment. Discuss with your doctor if joining is right for you.

Study details
    Asthma

NCT06529419

AstraZeneca

4 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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