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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Study on continuous monitoring for atrial fibrillation treatment options.

Recruiting
22-85 years
All
Phase 3

REACT-AF is a study for people aged 22-85 with a history of atrial fibrillation (AF), a condition where the heart beats irregularly. The study compares two ways of using Direct Oral Anticoagulants (DOACs), which are medicines that help prevent blood clots and strokes. Participants are divided into two groups: one takes DOACs continuously, while the other takes them for 30 days after AF episodes detected by a special smart watch (AFSW). The study lasts up to 60 months and involves 5350 participants at up to 100 locations.

  • Participation Duration: Up to 5 years.
  • Visits and Monitoring: Participants need to wear a smart watch and have a compatible smart phone.
  • Compensation: Details on compensation are not provided.

Eligible participants should not have permanent AF or certain health conditions, and must be willing to use a smart watch and comply with the study protocol. Those taking other blood thinners or having conditions that increase bleeding risk may not join. If you're interested, make sure you meet the criteria and can commit to the study requirements.

Study details
    Atrial Fibrillation

NCT05836987

Johns Hopkins University

20 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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