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Transcutaneous Electrical Nerve Stimulation in Chemotherapy Induced Peripheral Neuropathy in Patients With Stage I-III Early Stage Breast Cancer

Testing nerve stimulation for chemotherapy-related nerve pain in breast cancer.

Recruiting
18 years and older
All
Phase N/A

This study is about using Transcutaneous Electrical Nerve Stimulation (TENS) to help people with early-stage breast cancer who have nerve problems from chemotherapy. Chemotherapy can cause peripheral neuropathy, which means feeling pain, tingling, or numbness in the hands or feet. TENS uses mild electric currents on the skin to help relieve these symptoms.

Participants will use TENS at home for 1 hour each day for 14 days. The study checks if people can stick with this routine and if it helps their symptoms. It also looks at other treatments they might be using and any changes to their chemotherapy because of side effects.

  • Study involves daily 1-hour TENS sessions for 2 weeks.
  • Participants must be undergoing chemotherapy with drugs like paclitaxel or docetaxel.
  • Women must use birth control during the study if they can become pregnant.

This study is only for adults who can follow the study rules and have no conditions that could interfere with TENS. Participants should not have epilepsy, certain implants, or previous nerve issues. This is a chance to see if TENS can help with chemotherapy side effects.

Study details
    Anatomic Stage I Breast Cancer AJCC v8
    Anatomic Stage IA Breast Cancer AJCC v8
    Anatomic Stage IB Breast Cancer AJCC v8
    Anatomic Stage II Breast Cancer AJCC v8
    Anatomic Stage IIA Breast Cancer AJCC v8
    Anatomic Stage IIB Breast Cancer AJCC v8
    Anatomic Stage III Breast Cancer AJCC v8
    Anatomic Stage IIIA Breast Cancer AJCC v8
    Anatomic Stage IIIB Breast Cancer AJCC v8
    Anatomic Stage IIIC Breast Cancer AJCC v8
    Chemotherapy-Induced Peripheral Neuropathy
    Early Stage Breast Carcinoma
    Prognostic Stage I Breast Cancer AJCC v8
    Prognostic Stage IA Breast Cancer AJCC v8
    Prognostic Stage IB Breast Cancer AJCC v8
    Prognostic Stage II Breast Cancer AJCC v8
    Prognostic Stage IIA Breast Cancer AJCC v8
    Prognostic Stage IIB Breast Cancer AJCC v8
    Prognostic Stage III Breast Cancer AJCC v8
    Prognostic Stage IIIA Breast Cancer AJCC v8
    Prognostic Stage IIIB Breast Cancer AJCC v8
    Prognostic Stage IIIC Breast Cancer AJCC v8

NCT05368428

Emory University

27 April 2025

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