This study is comparing two ways to fix a heart valve problem. The heart valve, called the mitral valve, is not closing properly in people with a condition known as degenerative mitral valve disease. One group will have a less invasive procedure using a device called the Neochord DS1000 System, which does not require stopping the heart (no cardiopulmonary bypass - a machine that takes over heart and lung function during surgery). The other group will have traditional surgery where the heart is stopped and a machine helps. This study wants to find out which method is safer and works better.

• The study includes people with certain heart valve problems, but not those who had previous heart valve surgeries.
• Participants will be randomly assigned to one of the two groups.
• There may be risks involved, and participation is voluntary.

If you are considering participating, you should know that the study involves a heart procedure and you should talk to your doctor about potential benefits and risks.