Image

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

Testing Tofacitinib for kids with moderate to severe ulcerative colitis.

Recruiting
2-17 years
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing tofacitinib, a medication, in children 2 to 17 years old with moderate to severe ulcerative colitis (UC). UC is a disease that causes inflammation in the colon. The study wants to see if tofacitinib helps improve UC symptoms. In the United States and Europe, only patients who did not do well with previous treatments can join. All participants will start with a low dose of tofacitinib and may increase it if needed. The study will last up to about 180 weeks (over 3 years) and includes different phases: initial treatment, maintenance, and an extension period. Participants will visit the study site regularly and be monitored for any side effects.

  • Study duration can be up to 180 weeks with several phases.
  • Participants will start with a low dose of tofacitinib.
  • Regular visits for monitoring and follow-ups are required.
Print
Study details
    Ulcerative Colitis

NCT04624230

Pfizer

5 July 2025

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.