This study is for kids and young adults (12 months to 21 years) with tough-to-treat cancers like solid tumors, non-Hodgkin lymphomas, or histiocytic disorders. It uses genetic testing to find out if special medicines can help. Genetic testing checks the tumor cells' DNA for changes or mutations that might respond better to certain treatments.
Participants must have tried at least one standard treatment that didn’t work. The study involves taking a sample of the tumor and blood, and if a mutation is found, the patient will be assigned to one of several treatment plans. Treatment can last up to two years, with regular check-ups.
- Study Length: Up to 2 years with regular visits.
- Risks: Similar to other cancer treatments, risks include side effects from the drugs.
- Eligibility: Ages 12 months to 21 years, with specific types of cancer.
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