This study is testing how well a drug called **aficamten** works for people with a heart disease called non-obstructive hypertrophic cardiomyopathy (**nHCM**). This condition makes the heart muscle thicker than normal, which can make it harder for the heart to pump blood. The study will compare aficamten to a placebo, which is a harmless pill that doesn't have any medicine in it, to see if aficamten can improve life quality and exercise ability.
People who can join must be between 18-85 years old and have specific heart measurements showing nHCM. They should be able to exercise, like walking on a treadmill, and not have other serious heart problems. Important exclusions are certain heart valve diseases and other heart conditions.
- Study Duration: Participants will be involved for several months.
- Visits: Regular visits for check-ups and tests will be needed.
- Safety: Some risks may include reactions to the drug or exercise tests.
This study is important to learn if aficamten can help people with nHCM feel better and be more active.