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Pre-operative Atezolizumab in Patients with Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma

Studying Atezolizumab for treatable HPV-related throat cancer before surgery.

Recruiting
18 years and older
All
Phase 2

This study is testing a medicine called atezolizumab for patients with a specific type of throat cancer related to human papillomavirus (HPV). Atezolizumab is a type of immunotherapy, which means it helps your immune system fight cancer. In this study, patients will receive atezolizumab through a vein (intravenously or IV) and will have CT (computed tomography) scans and MRI (magnetic resonance imaging) to monitor their progress. Some may also have a biopsy, where a small piece of the tumor is taken for testing.

  • Study Duration: Patients will be followed for 2 years to check long-term effects.
  • Participation Requirements: Participants must be at least 18 years old, not pregnant, and use birth control. They must also have a confirmed HPV-related throat cancer.
  • Risks and Monitoring: Regular scans and possible biopsies will be done to monitor safety and effectiveness.

It's important for participants to understand the study's requirements and the commitment involved, such as regular hospital visits for treatment and scans. The study aims to see if this treatment is safe and effective in stopping the cancer from growing or spreading.

Study details
    Oropharynx Cancer
    Stage I

NCT06254911

Emory University

6 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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