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A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor

Trying a new medication for type 2 diabetes control.

Recruiting
18 years and older
All
Phase 3

This study is looking at how safe and effective a medicine called orforglipron is for people with Type 2 Diabetes (T2D). T2D is a condition where your body can't control sugar levels in the blood well. Participants in this study have T2D and their sugar levels are not well controlled with insulin glargine, with or without medications like metformin or SGLT-2 inhibitors (a type of medicine that helps kidneys remove sugar from the body). The study will last about 46 weeks and may require up to 20 doctor visits.

  • Time Commitment: The study lasts for around 46 weeks with up to 20 visits.
  • Eligibility: Participants need to have T2D, and have specific criteria for sugar levels and body weight.
  • Health Conditions: People with serious heart or liver issues or pancreatitis should not participate.

Before joining, consider if you can commit to the schedule and if your health condition fits the requirements. Always discuss with your doctor if you’re interested in participating in this study.

Study details
    Type 2 Diabetes

NCT06109311

Eli Lilly and Company

5 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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