This study is about understanding how cancer treatments, like radiotherapy, affect sexual health in women. Radiotherapy is a treatment that uses high-energy rays to kill cancer cells. Some women have side effects from this treatment that can affect their sexual life. The study aims to find out why this happens and how to reduce these side effects.

Participants will need to fill out Quality of Life questionnaires about their health and side effects. They will also give blood and microbiome samples (like stool) for research. These samples are collected before treatment, after treatment, and then every six months for two years. Participants might continue giving samples every year after that.

Eligibility for the study includes women who have cancer in certain areas like the cervix, uterus, or vagina, and are receiving pelvic radiotherapy. Some conditions might exclude you from the study, like if you've had certain surgeries or other health issues.

• Study lasts at least two years with some visits and samples taken.
• Participants answer health and side effect questionnaires regularly.
• No mention of direct compensation for participating.