This study is focused on infants with cholestasis, a liver condition where bile flow is blocked, causing jaundice (yellow skin and eyes) and high bilirubin levels in the blood. The main causes include biliary atresia, idiopathic neonatal hepatitis, and genetic disorders. The study aims to build a database of medical information and samples to help researchers understand and treat these liver diseases. Infants diagnosed with cholestasis will be monitored closely for the first year and then once a year until they are 20 years old or need a liver transplant. Blood and tissue samples will be collected for research purposes. Participation involves regular follow-up visits and tests, but helps advance knowledge on liver diseases.

• Participation lasts up to 20 years or until a liver transplant is needed.
• Includes regular blood tests and follow-up visits.
• No compensation mentioned, but contributes to important liver disease research.