Pancreatic Cancer Early Detection Consortium is conducting research to find better ways to detect pancreatic cancer early. Pancreatic cancer is a disease where cancer cells form in the pancreas, an organ that helps with digestion and blood sugar control. The study focuses on people with a family history of this cancer or those with certain gene changes, called pathogenic germline variants (PGVs), that increase the risk of developing it.

This is an observational study, meaning it does not involve any treatment or intervention. It involves collecting samples like blood every 6-12 months from participants who are at high risk. The samples are stored and shared with researchers to help them study and develop ways to find the cancer early.

Participants must be at risk due to family history or specific gene variants, be of a certain age, and provide samples like blood, saliva, or cheek swabs. The study is ongoing, and participants receive regular follow-ups with their doctors.

• Study involves regular collection of samples every 6-12 months.
• No treatment is provided; it is for research purposes only.
• Participants may have a family history or specific gene changes related to cancer risk.