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A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)

Exploring sensory stimulation for Alzheimer's in the Hope Study.

Recruiting
50-90 years
All
Phase N/A

This study is designed to test if sensory stimulation can help people with mild to moderate Alzheimer's disease, a brain condition that affects memory. **Sensory stimulation** includes activities that engage the senses, such as sight and sound. The study involves 600 participants who will receive either the real treatment or a fake (sham) one for 12 months. Researchers will measure progress using tests like the Alzheimer's Disease Cooperative Study - Activities of Daily Living (**ADCS-ADL**) and the Mini-Mental State Exam (**MMSE**). Participants will visit the study center several times over the year and will have some phone check-ins. Some participants will also provide fluid samples for additional research.

  • Study lasts for 12 months with multiple visits.
  • Participants must be between 50-90 years and have Alzheimer's disease.
  • No cost for participation, but some risks like lumbar puncture for fluid collection.
For more details, visit the Hope Study website.

Study details
    Alzheimer Disease
    Alzheimer Disease 1
    Alzheimer Disease 2
    Alzheimer Disease 3
    Alzheimer Disease
    Early Onset
    Alzheimer Disease
    Late Onset
    Alzheimer Disease 9
    Alzheimer Disease 4
    Alzheimer Disease 7
    Alzheimer Disease 17
    Alzheimer's Dementia Late Onset
    Alzheimer Disease 5
    Alzheimer Disease 6
    Alzheimer Disease 8
    Alzheimer Disease 10
    Alzheimer Disease 11
    Alzheimer Disease 12
    Alzheimer Disease 13
    Alzheimer Disease 14
    Alzheimer Disease 15
    Alzheimer Disease 16
    Alzheimer Disease 18
    Alzheimer Disease 19
    Dementia
    Dementia Alzheimers
    Dementia
    Mild
    Dementia of Alzheimer Type
    Dementia Moderate
    Dementia Senile
    Mild Cognitive Impairment
    Mild Dementia
    MCI
    Cognitive Impairment
    Cognitive Decline
    Cognitive Impairment
    Mild

NCT05637801

Cognito Therapeutics, Inc.

1 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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