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Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

Exploring cooling time effects on cardiac arrest recovery.

Recruiting
18 years and older
All
Phase N/A

This study is looking at how different lengths of time spent cooling the body help patients who are in a coma after a cardiac arrest. A cardiac arrest is when the heart suddenly stops beating. After this, a person might be in a coma, which is a deep unconscious state. In this trial, patients who have been cooled to below 34 degrees Celsius after cardiac arrest will have their cooling time adjusted randomly between 6 and 72 hours. Cooling helps protect the brain, but the best cooling time isn't known yet. This study aims to find that out.

  • This study lasts 90 days and involves follow-up assessments.
  • It is for patients over 18, cooled within 6 hours after cardiac arrest, and requires consent from a legal representative.
  • It excludes those with certain health conditions or planned early withdrawal of life support.

Participants will be monitored to see how well they recover neurologically within 90 days. This trial is crucial for improving survival and recovery after a cardiac arrest. Participants help advance medical understanding and treatment techniques.

Study details
    Cardiac Arrest
    Out-Of-Hospital
    Hypothermia
    Induced
    Hypoxia-Ischemia
    Brain

NCT04217551

University of Michigan

1 April 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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