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A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma

Testing NKT2152 for advanced clear cell kidney cancer.

Recruiting
18 years and older
All
Phase 1/2

This study looks at the safety and effects of a new medicine called NKT2152 for people with advanced clear cell renal cell carcinoma (ccRCC), a type of kidney cancer. The study has two parts. In Phase 1, doctors will find the best dose for patients by giving the medicine once a day. In Phase 2, they will study how well the medicine works and how safe it is.

To join, patients must be 18 years or older, have advanced ccRCC that has not responded to standard treatments, and be able to swallow pills. They must also have a life expectancy of at least 3 months and meet other health criteria.

  • **Study Duration**: Participation involves multiple visits over a few months.
  • **Risks**: There might be side effects, as this is a new treatment.
  • **Eligibility**: Patients must meet specific health and treatment criteria.

This study offers patients who have no other treatment options the opportunity to try a new therapy that may help manage their cancer.

Study details
    ccRCC
    Clear Cell Renal Cell Carcinoma
    Kidney Cancer
    Kidney Neoplasms
    Renal Cancer
    Renal Neoplasms
    Recurrent Renal Cell Carcinoma
    Metastatic Renal Cell Carcinoma
    Refractory Renal Cell Carcinoma
    Advanced Renal Cell Carcinoma
    Hypoxia
    Renal Cell Carcinoma
    Hypoxia Inducible Factor (HIF)
    HIF2α Inhibitor
    Hypoxia Inducible Factor 2 Alpha (HIF-2 Alpha)
    Hypoxia Inducible Factor 2α (HIF-2α)
    Clear Cell

NCT05119335

NiKang Therapeutics, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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