This study is testing the safety and effects of a treatment called tumor treating fields (TTFields) for people with brainstem gliomas, a type of brain cancer. TTFields use low-intensity electrical fields to stop cancer cells from dividing. Patients will wear a device called Optune for at least 18 hours each day for up to 12 months. The study also combines TTFields with common treatments like radiotherapy (radiation) and chemotherapy (cancer-fighting drugs).
Key Points:
- Duration: The study lasts 12 months with follow-ups every 3-6 months afterward.
- Visits: Patients will have check-ups at 3, 6, 9, and 12 months during treatment.
- Eligibility: Must be 18 or older with certain health criteria and agree to use birth control if needed.
Participants will be monitored for the effects on their tumor and any side effects. The study aims to see if TTFields can help prevent tumor growth and improve overall survival. Eligible participants need to have a life expectancy of over 12 weeks and meet certain health conditions. Women must take a pregnancy test before starting. The study excludes those with certain health issues or who have used investigational drugs recently.