Prehospital Airway Control Trial (PACT) is a 5-year study involving emergency medical professionals who assist trauma patients before they reach the hospital. In this trial, some patients will receive usual care (normal treatment) while others will receive a different method called a supraglottic airway management approach. The main goal is to see if patients survive 24 hours after treatment. Other factors like time in the ICU (Intensive Care Unit) and days on a ventilator are also studied. The trial will involve around 2,009 patients across 17 locations.

Patients can join if they have a serious injury needing advanced airway help. They must be transported to a participating trauma center. Kids under 15, pregnant women, and prisoners can't join. Also, if someone already tried an advanced airway or if there's no heartbeat, they can't participate. If a patient or family says no, they are also excluded.

• The study lasts 5 years and involves multiple visits.
• Randomized to usual care or new airway method.
• Survival and other health outcomes are measured.