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AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

Join the AHEAD study for Alzheimer's treatment research with Lecanemab.

Recruiting
55-80 years
All
Phase 3

The AHEAD 3-45 Study is looking at how well the drug lecanemab works and how safe it is for people who might be at the very early stages of Alzheimer's disease. Alzheimer's disease is a brain disorder that affects memory and thinking. In this study, researchers want to see if lecanemab can help keep the brain healthy and slow down changes seen in Alzheimer's. The study will last for about 216 weeks, which is a little over four years, and includes multiple tests and check-ups.

Key Points:

  • Duration: The study lasts for about 4 years, with regular check-ups.
  • Eligibility: Participants should be between ages 55-80 and meet certain health criteria.
  • Safety: The study will evaluate the long-term safety of the treatment.

Participants will need to have a study partner who can help provide information about their daily activities. They should not have certain health issues like recent strokes, or certain metal implants that can interfere with MRI scans. If you meet the criteria and are interested, this study could help advance understanding and treatment of early Alzheimer's disease.

Study details
    Preclinical Alzheimer's Disease
    Early Preclinical Alzheimer's Disease

NCT04468659

Eisai Inc.

12 October 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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