The CLUE study examines how doctors use EsoGuard test results to decide if a patient needs an endoscopy. An endoscopy is a test where a doctor looks inside your throat and stomach with a special camera. The study uses real-world data from patients who had tests with the EsoCheck device. It checks if patients follow doctor recommendations for an upper endoscopy after EsoGuard results. The study focuses on those who need screening for Barrett's Esophagus (BE), a condition where the lining of the esophagus changes, using guidelines from the ACG (American College of Gastroenterology) or AGA (American Gastroenterological Association).

• Study involves screening with EsoGuard and EsoCheck.
• Participants must meet specific guidelines for BE screening.
• Participants must be able to provide consent and follow up with doctors.

Before joining, ensure you understand the study requirements and check if you meet the guidelines for Barrett's Esophagus screening.