This study is for people with a BRCA1 gene mutation, a genetic change that increases the risk of ovarian cancer. It compares two surgeries to see which one reduces cancer risk better. One is called bilateral salpingectomy (BLS), where the fallopian tubes are removed. The other is bilateral salpingo-oophorectomy (BSO), where both the fallopian tubes and ovaries are removed. The study helps doctors find out if BLS is as effective as BSO in lowering cancer risk.

• The study includes regular follow-ups for up to 20 years after surgery.
• Participants may experience symptoms from reduced estrogen, like menopause symptoms, especially with BSO.
• A pelvic ultrasound and blood tests will be done during the study.

To join, you must be 35-50 years old and have a BRCA1 mutation. You can't join if you've had certain cancers or abnormal screening tests recently. The study requires informed consent, meaning understanding the risks and benefits before deciding to participate. Remember, if you have the surgery, you won't be able to have children naturally afterward.