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Clinical Study of Antibody-Drug Conjugate MYTX-011 in Subjects With Non-Small Cell Lung Cancer

Exploring MYTX-011 for non-small cell lung cancer treatment.

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing a new drug, MYTX-011, for people with Non-Small Cell Lung Cancer (NSCLC), a type of lung cancer. MYTX-011 is an antibody-drug conjugate (ADC). This means it combines an antibody, which finds cancer cells, with a strong drug, monomethyl auristatin E (MMAE), which kills those cells.

The study has two parts: Part 1 checks if the drug is safe and helps find the right dose. Part 2 tests how well the drug works in people with specific gene changes in their cancer. To join, you must have advanced NSCLC and have tried other treatments before.

  • The study might involve multiple visits to centers and it checks if the new drug is safe.
  • Participants must have a specific type of lung cancer and may have had other treatments before.
  • There is no compensation mentioned, and the study may carry some risks.

It is important for participants to be able to follow study rules and use effective birth control during and after the study. Anyone interested should discuss participation with their doctor to understand the potential risks and benefits.

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Study details
    NSCLC
    NSCLC Stage IV
    NSCLC Stage IIIB
    Non-Small Cell Lung Cancer
    Advanced Non-Small Cell Squamous Lung Cancer
    Advanced Non-Small Cell Lung Cancer
    Advanced Non-Small Cell Non-Squamous Lung Cancer

NCT05652868

Mythic Therapeutics

31 March 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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