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A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin

Comparing Orforglipron and Dapagliflozin for Type 2 Diabetes management.

Recruiting
18 years and older
All
Phase 3

This study is for adults with type 2 diabetes (T2D), who haven't been able to control their blood sugar well with metformin, a common diabetes medicine. The goal is to compare two drugs: orforglipron and dapagliflozin, to see which helps more in managing blood sugar levels. The study will last about 46 weeks, which is a little less than a year. People who join will need to have a certain blood sugar level and be taking a stable dose of metformin. They also need to keep their weight steady without starting a new diet or exercise program.

  • The study lasts about 46 weeks.
  • Participants should keep their weight steady.
  • They will be comparing two medicines for managing blood sugar.

Some people cannot join, like those with Type 1 diabetes (T1D) or certain other health conditions. This study will help find the best treatment for people with T2D who need better blood sugar control.

Study details
    Type 2 Diabetes

NCT06192108

Eli Lilly and Company

5 January 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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