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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

Study on Dalcetrapib's impact after recent heart attack in specific genes.

Recruiting
45 years and older
All
Phase 3

This study looks at how a drug called **Dalcetrapib** affects heart health in people with a special genetic makeup who recently had an Acute Coronary Syndrome (ACS) event, which means a sudden heart problem. Some people will get a placebo, which is a fake pill with no medicine, to compare results. The study is "double-blind," meaning neither the doctors nor the participants know who gets the real drug or the placebo.

To join, you must be 45 or older and have a specific genetic type known as **AA genotype**. You should also be stable without severe heart symptoms for at least a week. The study will last until 200 people have a main heart event. Visits will be virtual every 3 months if possible, or in a clinic.

  • **Length**: Lasts until 200 events occur.
  • **Visits**: Every 3 months, mostly virtual.
  • **Compensation**: Not specified.

Pregnant women or those with certain health issues, like severe heart failure or high blood pressure, cannot join. No recent participation in other drug studies is allowed.

Study details
    Acute Coronary Syndrome

NCT05918861

DalCor Pharmaceuticals

27 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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