This study tests a new treatment called **IDP-023** for people with serious blood cancers. Blood cancers are diseases where the blood cells grow out of control. IDP-023 uses "natural killer" cells. These are a type of white blood cell that can attack cancer cells. In this study, IDP-023 is given alone or with other treatments like interleukin-2 (IL-2), isatuximab, daratumumab, or rituximab. The study has two parts:
Phase 1 - Checks if the treatment is safe and finds the best dose. Phase 2 - Tests how well the treatment works.
**Key Points**:
- This study is only for patients with advanced multiple myeloma (MM) or non-Hodgkin's lymphoma (NHL) who have tried other treatments without success.
- Participants must not have serious heart issues, infections like HIV, or untreated brain cancer.
- Participants should be able to do normal daily activities and have a life expectancy of more than 12 weeks.
People considering this study should know it involves multiple visits and tests to monitor safety and effectiveness.