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A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

Testing Dostarlimab vs Placebo after chemoradiation for head and neck cancer.

Recruiting
18 years and older
All
Phase 3

This study is testing a drug called Dostarlimab against a fake medicine called a Placebo for people with a type of head and neck cancer called HNSCC (Head and Neck Squamous Cell Carcinoma). Dostarlimab is a medicine that helps the immune system find and attack cancer cells. To join, patients must have a new diagnosis of HNSCC that cannot be removed with surgery, and they must have finished treatment with a drug called Cisplatin and radiation. They must also have good organ function and not have cancer in other areas like the nose or sinuses.

  • Participants must have completed specific cancer treatments before joining.
  • Exclusion for those with certain other medical conditions or past treatments.
  • Participants cannot be pregnant or planning to have children soon.

This study helps doctors understand more about how well Dostarlimab works and how safe it is for treating this type of cancer. If you're eligible, it's important to know there might be risks, and you should discuss with your doctor if this study is right for you.

Study details
    Neoplasms
    Head and Neck

NCT06256588

GlaxoSmithKline

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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