Image

Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity

Join a study on upper limb spasticity treatment with Iovera®°.

Recruiting
18 years and older
All
Phase 3

This study examines how well the **Iovera®° system** helps people with **upper extremity spasticity** (muscle stiffness in the arm). The study will include 132 people: 88 will get the actual treatment, and 44 will receive a pretend treatment (placebo). The Iovera®° system targets nerves with a special device, using a local numbing medicine called *lidocaine*. The main goal is to see if this system can reduce muscle stiffness safely. Participants will be in the study for 13 weeks, with check-ins at 3, 7, and 13 weeks.

Eligibility: Participants must be 18 or older, have a stable muscle stiffness condition, and not have had certain treatments recently. They should be able to follow the study schedule and provide consent.

  • **Duration**: 13 weeks with multiple follow-up visits.
  • **Treatment**: Some will receive Iovera®° treatment; others will get a placebo.
  • **Eligibility**: Must be 18+, have stable spasticity, and follow the schedule.
Study details
    Spasticity
    Cerebral or Spinal Condition

NCT06340451

Pacira Pharmaceuticals, Inc

25 May 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race
Ethnicity
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.