This study is testing a new medicine called **tecovirimat** for treating **Mpox virus** (HMPXV). Mpox is a disease caused by a virus that can give you sores or lesions on your skin or in your mouth. **Tecovirimat** is being tested to see if it can help people get better faster. The study will include 530 people to see if the medicine works better than a fake pill, called a **placebo**. Some people will get tecovirimat openly, meaning they know they're taking the real medicine. This includes those who are pregnant, breastfeeding, under 18, or have severe cases.

The study lasts for **14 days** of taking the medicine, but you'll be checked up until **day 57**. You will need to keep a daily diary about your symptoms and pain. You will also visit the clinic every week to see how you're doing. If you get worse, the doctors will change your treatment to make sure you get the help you need.

• You will be monitored for up to 57 days.
• Weekly clinic visits are required.
• Special care for severe cases and specific groups, like kids and pregnant women.