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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Exploring prostate cancer treatments with or without standard therapy.

Recruiting
18 years and older
Male
Phase 3

This study is for men with metastatic prostate cancer. This means the prostate cancer has spread to other parts of the body. The study is examining if adding surgery or radiation to the usual treatment helps patients live longer and stops the cancer from growing. Usual treatment, known as Standard Systemic Therapy (SST), involves medications or hormones that affect the whole body. Participants will be randomly chosen to receive either just SST or SST plus surgery or radiation.

  • Time Commitment: Participants will be followed for 8 years after treatment.
  • Treatment: Includes different types of hormone therapies and possibly surgery or radiation.
  • Eligibility: Participants must have prostate cancer that has spread, but without brain involvement, and should not have had local prostate cancer treatment before.

The study also looks at how the treatments affect quality of life, like urinary function and pain. Participants will have multiple visits and tests throughout the study. There are no emojis in this summary to keep it professional and informative.

Study details
    Castration Levels of Testosterone
    Metastatic Prostatic Adenocarcinoma
    Stage IV Prostate Cancer AJCC v8
    Stage IVA Prostate Cancer AJCC v8
    Stage IVB Prostate Cancer AJCC v8

NCT03678025

SWOG Cancer Research Network

13 December 2024

Step 1 Get in touch with the nearest study center
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  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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