This study is testing a new drug called **VE303** to see if it can help stop Clostridioides difficile infection (CDI) from coming back. CDI is a type of bacterial infection that causes diarrhea and belly pain. The study will compare **VE303** with a placebo, which is a fake treatment used to see if the real treatment works better. The study lasts **8 weeks**.
Key Points:
- **Participants must be 12 years or older** and have had CDI before. There are special rules for different age groups, especially for those 75 years or older.
- **Participation includes taking the study drug for 14 days** after completing a standard antibiotic treatment for CDI.
- You cannot join if you have certain health conditions like chronic diarrhea, or if you've had specific treatments for CDI before.
This study is looking for people who have had CDI before or are at a high risk of getting it again. It's important to talk to your doctor to see if joining this study is right for you. You will be closely watched to see how well the treatment works and if there are any side effects.