Study Summary: This study involves collecting tissue samples for cancer research from patients at the NIH Clinical Center and other participating sites. The samples help scientists understand cancer better and develop treatments. These samples may be obtained from tests and procedures already being done as part of patients' care or from specific procedures like biopsies.

Key Points:

• The study includes both adults and children who are undergoing cancer evaluation or treatment.
• Samples collected include blood, urine, tumor tissue, and more. Procedures like biopsies will be discussed in detail with patients and guardians.
• Participation may last for the duration of consent or until the planned procedure is completed.

Eligibility:

Adults and children with cancer, receiving care at specific centers, can participate. Some restrictions apply, like not having certain infections.

For adults, samples may include blood, urine, and tissue. For children, samples are from procedures needed for their care. Note: All procedures and risks will be explained beforehand, and consent is required.