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A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

We're studying a new treatment for nerve pain from chemotherapy.

Recruiting
21 years and older
All
Phase 2

This study is testing a drug called Tetrodotoxin (TTX) for treating neuropathic pain (nerve pain) caused by chemotherapy, a treatment for cancer. The study is randomized and double-blind, meaning neither the participants nor the researchers know who is getting the real drug and who is getting a placebo (a harmless pill with no medicine). To join, you must be 21 or older, have stable, moderate to severe pain from past chemotherapy, and not have any actively growing cancer.

The study lasts for about 13 weeks, including a 4-day treatment and weekly follow-ups. You must not have other types of neuropathy (like from diabetes) and must not take certain medications that may interfere with the study. It's important to discuss with your doctor if you have other medical conditions or are taking other medications.

  • The study lasts for 13 weeks, including treatment and follow-ups.
  • Participants need to have stable moderate to severe pain from past chemotherapy.
  • Certain medications and medical conditions can exclude you from joining.
Study details
    Chemotherapy-induced Neuropathic Pain
    Chemotherapy-induced Peripheral Neuropathy

NCT05359133

Wex Pharmaceuticals Inc.

13 December 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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